In South Africa, the six years since 1994 have been characterized by the need tounderstand and shape the future of this country and my Ministry has initiated a range of initiatives aimed at meeting this objective. In the science and technology field these initiatives include the White Paper on Science and Technology, the National Research and Technology Audit, the Review of Science and Technology Institutions and the National Research and Technology Foresight (NRTF).The Science and Technology White Paper, published in 1996, was based on the twinconcepts of innovation and a national system of innovation (NSI). The NRTF report is an important milestone that allows us to put real content into the NSI and thereby develop a framework of goals within which our technology programmes can be shaped. NRTF findings indicate a decline in the resource-based economic activities such as mining, primary agriculture and traditional manufacturing. In contrast, new developments in biotechnology, information and communications technologies and new materials signal the future ascendancy of a knowledge-based economy. The wealth of biological diversity in South Africa and our immense tourism potential have, as in other studies, been identified as focal points for growth.There are a number of challenges that need to be overcome though. The humanresources skills base and the ability to commercialise the new emerging technologies remain major obstacles. These challenges remain the priorities of this Ministry. However, the involvement of approximately 5 000 South African stakeholders in the NRTF offers hope in that we have created cohesive networks of our best minds as byproducts of the process. These networks, now accustomed to thinking analytically about ..